Squamous cell carcinoma (SCC) is the second most common form of skin cancer and frequently arises on the sun exposed skin of middle aged and elderly individuals. General risk factors associated with the disease are: age more than 50; male sex ; fair skin; location closer to the equator; history of prior non-melanoma skin cancer or human papilloma virus infection; high exposure to ultra violet light, chemical carcinogens and ionizing radiation; and chronic immuno-suppression or a scarring condition. A cumulative life time sun exposure and immuno-suppression are primarily believed to be the cause of this condition. A typical SCC lesion is a raised, pink-to-flesh-colored papule or plaque arising on sun exposed skin. Surgery, local chemotherapy, photo-dynamic therapy and radiation therapy are the standard line of treatment for this condition.